Clonazepam – Uses, Side effects, Precautions

Clonazepam is a derivative of Benzodiazepines which treats various types of seizures (fits) i.e typical absence (fits appear suddenly and go off), infantile myoclonic (jerks caused by sudden muscle contractions in children), atypical absence (resulting in sudden loss of attention), myoclonic (jerks caused by sudden muscle contractions) and akinetic seizures (complete loss of muscle tone).

Used for Hypnotic, sedative, antiepileptic or anticonvulsant, antianxiety, muscle relaxant and alcohol withdrawal
Dosage forms Tablets, Oral disintegrating (dissolving) tablet, Oral solution
Available Strengths 0.5mg, 1mg, 2mg, 0.125mg, 0.25mg, 0.5mg.
0.5mg/5ml, 2mg/5ml oral solution (for pediatrics)
Method of administration Taken with or without food orally
Prescription Required
Alternatives Klonopin, Azepic, Clonafit, Clonamed, Clonotril, Clozep, Epitril, Epizam, Lonazep,Melzap, Norep,Ozepam, Sezolep
Pharmacokinetics Onset of action : 30 to 40 minutes
Duration of action 6 to 8 hours in adults and 12 hours in children
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Modalert – Uses, Dosage, Precautions, Interactions

Modalert (Modafinil)

Used for Narcolepsy, Obstructive sleep apnea, Shift Work Disorder
Dosage forms Tablets
Strengths 100mg, 200mg
Method of administration Taken with or without food orally
Prescription Required
Alternatives Alertec, Alertex, Altasomil, Aspendos, Forcilin, Intensit, Mentix, Modafinilo, Modanil, Modasomil, Modvigil, Modiodal, Modiwake, Movigil, Provigil, Resotyl, Stavigile, Vigia, Vigicer, Vigil, Vigimax, Wakelert and Zalux
Pharmacokinetics Onset of action : 2-4 hours
Duration of action : For highest strength it is upto 8 hours

Indications and Clinical Use

  • Indicated for the treatment of excessive sleepiness (Narcolepsy) in adult patients, shift work type disorder (i.e people working in shifts having irregular sleep cycle) (SWD).
  • Also indicated for the treatment of Obstructive sleep apnea (OSA) ,a sleeping disorder, where breathing suddenly stops for a short time during night.
  • Used for the treatment of hypersomnia (excessive daytime sleepiness).

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