Duphaston – Uses, Dosage, Side effects, Precautions

Duphaston is a synthetic derivative of a female hormone progesterone. It is used to treat menstrual irregularities in people more than 18 years of age. It is also used to prevent miscarriage and abortions. It contains active ingredient didrogesterone.

Used for Dysmenorrhea, threatened abortions, menstrual abnormalities, infertility problems, uterine bleeding and hormone replacement therapy
Dosage forms Tablets
Available Strengths 10mg, 20 mg and 30 mg
Method of administration Taken during night time after dinner
Prescription Required
Alternatives Dabroston, Terolut, Dufaston
Pharmacokinetics Onset of action: occurs within 0.5 to 2.5 hours of drug administration
Duration of action: within 24 hours
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Quadriderm Cream – Usage,Dosage, Side effects, Precautions

Quadriderm is a topical (applied to skin) dermatological preparation which belongs to a class of steroids. It is a combination of drugs like Betamethasone, Gentamycin, tolnaftate and clioquinol. It is used for treating various skin disorders like microbial infections, fungal infections, dermatitis, eczema, Psoriasis of scalp, feet and hands, Pruritus and groin ringworm infections.

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Kenalog Cream – Uses, Side effects, Dosage, Precautions

Kenalog Cream contains Triamcinolone Acetonide as an active ingredient. It is a corticosteroid hormone and is chemically 9α-fluoro-11β, 16α, 17α, 21-tetrahydroxypregna-1, 4-diene-3, 20-dione.

What is it used for?

It is used for the treatment, control, prevention of diseases & conditions like

  • Dermatitis
  • Eczema (itchy inflammation of skin)
  • Stomatitis (inflammation of mucous membrane of mouth)
  • Rheumatoid arthritis
  • Osteoarthritis
  • Skin irritation and rashes
  • Inflammation and pruritis
  • Psoriasis (scaly and itchy dry patches on skin)
  • Certain cancers
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Spasmed – Uses, Side effects, Precautions, Interactions

It is used for the treatment of various types of pains. Spasmed is a combination of Dicyclomine and Paracetamol. Dicyclomine is an anticholinergic drug which reduces muscle contractions (spasms) and Paracetamol is a non-steroidal anti-inflammatory (NSAID) drug which reduces pain

Therapeutic class Antispasmodic, Anti-inflammatory
Used for Irritable Bowel syndrome, Joint pain, Headache, Fever, Period pains, tooth pains, cold, ear pain, Flu
Dosage forms Tablets, Suspension, Injection
Available Strengths 10mg/250mg, 20mg/500mg, Oral suspension 30ml
Method of administration With or Without Food
Prescription Required
Alternatives Cyclopam, SPASMO FORTE injection, Colimex, Colinol, Colipen
Pharmacokinetics for Dicyclomine Onset of action: 1 to 2 hrs
Duration of action 4 to 86 hours
Pharmacokinetics for Paracetamol Onset of action: 30 to 60 minutes
Duration of action 6 hours

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Clonazepam – Uses, Side effects, Precautions

Clonazepam is a derivative of Benzodiazepines which treats various types of seizures (fits) i.e typical absence (fits appear suddenly and go off), infantile myoclonic (jerks caused by sudden muscle contractions in children), atypical absence (resulting in sudden loss of attention), myoclonic (jerks caused by sudden muscle contractions) and akinetic seizures (complete loss of muscle tone).

Used for Hypnotic, sedative, antiepileptic or anticonvulsant, antianxiety, muscle relaxant and alcohol withdrawal
Dosage forms Tablets, Oral disintegrating (dissolving) tablet, Oral solution
Available Strengths 0.5mg, 1mg, 2mg, 0.125mg, 0.25mg, 0.5mg.
0.5mg/5ml, 2mg/5ml oral solution (for pediatrics)
Method of administration Taken with or without food orally
Prescription Required
Alternatives Klonopin, Azepic, Clonafit, Clonamed, Clonotril, Clozep, Epitril, Epizam, Lonazep,Melzap, Norep,Ozepam, Sezolep
Pharmacokinetics Onset of action : 30 to 40 minutes
Duration of action 6 to 8 hours in adults and 12 hours in children

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Modalert – Uses, Dosage, Precautions, Interactions

Modalert (Modafinil)

Used for Narcolepsy, Obstructive sleep apnea, Shift Work Disorder
Dosage forms Tablets
Strengths 100mg, 200mg
Method of administration Taken with or without food orally
Prescription Required
Alternatives Alertec, Alertex, Altasomil, Aspendos, Forcilin, Intensit, Mentix, Modafinilo, Modanil, Modasomil, Modvigil, Modiodal, Modiwake, Movigil, Provigil, Resotyl, Stavigile, Vigia, Vigicer, Vigil, Vigimax, Wakelert and Zalux
Pharmacokinetics Onset of action : 2-4 hours
Duration of action : For highest strength it is upto 8 hours

Indications and Clinical Use

  • Indicated for the treatment of excessive sleepiness (Narcolepsy) in adult patients, shift work type disorder (i.e people working in shifts having irregular sleep cycle) (SWD).
  • Also indicated for the treatment of Obstructive sleep apnea (OSA) ,a sleeping disorder, where breathing suddenly stops for a short time during night.
  • Used for the treatment of hypersomnia (excessive daytime sleepiness).

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